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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb6f87b0d9e371ba0d42b3220e098b122156bef49712b10936a4cb8166fefb4' 
  AND token = 'JWE2MHiX9vKobqlC6vxoM2yuVyh176VInSaw3zWpUIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}