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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4f7ead58f4587c598817c01723a5e21ceb00d22575ae70bc50fb8623341f69a' 
  AND token = 'cRPT2VN3g8+ZosOaEOI23AOsWZQhsNR8yRoxeV1wrL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}