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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246f5c221491430ea097fb520b75ad8d1b20b27f843633c7ffecb52e77e12f66' 
  AND token = 'GhQe4uc4sie7QvyMt1OLjZxxDg7CmzHmZ0l+w2+7bBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}