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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8774c2c1a223243cf6747c8befdf6cee7ee06147af387e092fa2f8d0d89b5b1d' 
  AND token = 'Yz+ekQdDLLBxTKaD77RWXUYWFwylO8N0LcExbs+DokE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}