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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21178d32c794fc2811292d067360e174893822736e7d2c20be675b7fe1569ed4' 
  AND token = 'eaKY7VWEH19GbCuf65GcOpqPXhU2XGOLUUDxe9FE9C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}