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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e777be2003bc9a953ca38bd357c4e993e0816794c3bbdd306e0b2427271b8171' 
  AND token = 'ELeD/eu4ht/3WLi7sf2YfVasnnKujUKk7cadyZKX614=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}