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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49b230827075ed413d34e48fcad1c20a81956bd312a815afebca89e28f438aa' 
  AND token = 'z2t6EcBYZulFBrcJmq5C4EJ65rJQNcHrJyuq+6wtKSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00107

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}