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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df3fe52a95a3ce03f98e3aa892074c9910602a4e6496db31fb4a56a08fece58' 
  AND token = 'JG5uen+wOOEB66GMiFuL6fZW2dXT1khpGPVyfAThdAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}