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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8da180158df962921c1324fbe734e1273d84b4de2b4036bd10c6030b04d85f0a' 
  AND token = 'hPZiSdt+1B6TrpUZ9p6mMc+7PNuc03X9ntWuSZxiVo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}