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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3136d90fa40ce5f862f3a55f32d89a6b010cfcf98a9febf9b2c20112f52cbce1' 
  AND token = 'fDkuyzTL7gIcQV6Pr100VzRiDV1JbKhQoUTE8eMpwXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}