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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e37ecb3e86c9ecea66161a6f16834a97463d14a8c9db151b1ab78096986adacb' 
  AND token = 'L7iroB2VRjy8YSWLhmjEdvn/TCaV/8h2QwBfzpR2gL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}