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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0578c2d270cfa8cf442707ba2e2e487a32045f45e8c92013a3b74d6f54aba13f' 
  AND token = 'lfA/yW9pcyNRuc4gGwxYGBj5FuPt1qXwI+6PEa+a/KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}