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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bff16f146820d4bc3e71f619996eb38bedf23f4c6b692f19e739f9b2fad5e248' 
  AND token = '/mE0+DeYb4q0VKYBo/ETfTTioKRDV4qQHmddbUofFnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}