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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16270659ad7ac2cc7bcd7253aa351023d1dda98f4ad9b40c457463bbf4d9046' 
  AND token = 'V9Eyid9Ax+JxrCW8BwKpq15p6WLTEhacn9O5yowCsUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}