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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e5d6a65ee3cc19dd62a35bee3592921bdee2b3dc57025a60004552d1fbc0e2' 
  AND token = 'u5ZTT+VJXIyISlsfz4Ee9+77n7hFVTGujbG/b9HF1TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}