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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c34328513838897c3e0c5f7d60de5fe436e6f4d7349933d1a9767dd298c2353d' 
  AND token = 'r3ntcqBw60otMSFVjKb3kIVy+QmIrxFVAo4xZbk7iRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}