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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c49c622d3470d0f28a0b48a97b9d5f571134be99719a5a25276b91ec3640f7b' 
  AND token = 'PD1DyfUd1u5nPV9vr4AsEeG/yBJ7C0g2fcs9jS8hMjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}