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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb0649d0cb1209d4b932d64b61bcf124284a8c0834bdf6d8f2ce69494ddb115' 
  AND token = 'HrgtDGmhLcUggHlq0NlUnZOqwOc4sPOhMzu5tDeYc0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}