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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4d1ad8b080649810a1200a6703f65ce6fd56f427b0c24fb72351196074a7c3' 
  AND token = 'wr4yC5DON1/OmU90QvLKCEoAcMHSNy3u8frUN6PpFWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}