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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebc603b1e7fee60940b7f7bd173f538f109d14972052d8ae7f96a5641df3d8a8' 
  AND token = 'ht58xeQAW+5QiRGnQ0bZjjrwPWOtTb6nCsWLepDwN1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}