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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3645e5c96662583a6a240b4bc8b892d25187fcaae5833ebef6b1d3ea6427d9e' 
  AND token = 'ee0NZ01NBZXtrjoOKlACrCaXi0brHankEjVRgYne7G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}