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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d7727bd812a7cd4112c12696a3f86885e176d13bb8052142cc847bb18a10fe' 
  AND token = '7YUGX/CRMF+hPWclg6DSe82Fw2m1yrZBtvbK6lNLPTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}