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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd437a11217b32340e85b2269fe4409c98af20e8c1c113da8b36b3b520a94d815' 
  AND token = 'dWeHcScosHCB4h6rUiNbsZm16KfX1x+P2cC7NL3usgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}