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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9d156a6a2cf5ee0febe0ce4b018027d917a593b8ac96a8be1f29e589ca749a7' 
  AND token = 'FV3QMUm2KbXlxlGvZWrTZkTf/Uvd6gigEn3LhWZFz0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}