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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd89a53d8a824fa51f9b0171c3f646d98789b7ba18375e8711c5a6db9370a6109' 
  AND token = 'lu/WfA9wPxG96gE5XkoGFn3yNGlajYR97ZSjcki3SJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}