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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434438961e3b8c8722d3108d1a19852a2e993be3c0b0efb096640043427c5a28' 
  AND token = '5D0Vexkm8t47dUVfYajZ0VKoNrJKUFIAby1pJDVXOAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}