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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1e0145042525fb84573c1cbcec3ab253f1636f5cf99513c12f3f56dddeaf7ce' 
  AND token = 'MVTjiA+7+uE+/n8yGcDab1VlDqglmmNRIkrRFVjffQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}