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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c901cbdc890f8468e748d67ccacd35df5ddb3de92544e09ecec62208284c28' 
  AND token = 'f9TUI93GEaD+7Ol9k3xhqzrvUwxeSSPDs+mUj/Z651k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}