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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49618beb083e6575fb94efe615921109e69bc3b04f5cd4ab9d4a60630936e263' 
  AND token = 'S4/Tl8b1p6xS9ikAwBBjVkF0304YSI2u/h0Uf472tX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}