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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff7c72866fdd077d609621b7a2a847d471162eebd7e8b6a7422f2cad1e94c49' 
  AND token = 'AOJE6OoLy4NNZJoYLqW6UJ53eMjYOPdiforw1H9ITr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}