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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25f60b74fc8917ebef72100cf1ab9373b775587ec779ee67d02c9219163e65f' 
  AND token = 'p7w7Sq4Rpui/LrvJJ1jgYB0Y10BossLWANK2NATVoOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}