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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6eb568d59ce5a502d6205a91afe8f7f3eaf441ea70e2a87462d40fbf7d792f0' 
  AND token = 'hcIXKEdeZpCE8jL0sVzWXoTXTmZ06MHYHFU0IkWWa/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}