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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2500157cb42bce3b963f2a00f891a06f3f1a576a960e938aa99e63a8c5a3ab34' 
  AND token = 'Wo4ecmZ2V4X+9n1NPxNym+DduzIv8W2KPMFtxv1NZfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}