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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a45599747a8bd571360b52e44b2d696c0c874b0d69a2fa85c0d08fbaadad173' 
  AND token = 't8k6PMaWgKB2lIsgG7lrJnMBfReU7hMVyVSo1Wm+6u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}