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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3494337c6a3929c5c4c1b2466d3d7c29b0caddb0f1bd53d500084d1306b039be' 
  AND token = 'HIVt44qmj1iKkIicXJJMOreC4XOuou3SeqbdzRcpQd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}