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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46806e2e05d6d9dd1a91233cf3a911bf29a618665b31929eda2c41494fb35e74' 
  AND token = 'k20KrQK3d4AVyFBCmj+6V50RY51tYSUqn0qYtclSukE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}