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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '867554912942aa26416c9871cb9b073070c5b012aa3fadad363563be7b8ccdd1' 
  AND token = 'ebcl12fi5+N8Tczy0o0ZQi64QqlwtNJLpL5xMo7uFUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}