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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7335f5ad3db71bf92b51c026a16260a594cb9da85ae34e2c8ac23500074747' 
  AND token = 'q4BJyL53qXjCBPLL1X6lNDa/wXThDmx/NDHW33iJ1bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}