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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3fb8555d052e54828807cc01f2ed718acb8a66693e678f52877301b005baee6' 
  AND token = '9GcKHSHOs3Hs8BLO/G+Y3dUDoTp+lQWpR9INyvgup9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}