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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a06de571e75c9957a14f4169fa9f07a3f1a4b83f554f6540546e6c88641f8de8' 
  AND token = 'I7g1eE/8BzGxYTE5YuyXr5mX60ZfPiqJZiRz8XT2aGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}