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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaaf5e592110a16986240572476472127ef81f394ddc8b8a2a7217856ec1256f' 
  AND token = '7m7rswq2E7IAryW886nMcW+0g3oiCXugeSdpyWnZiOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}