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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33285ec43ec6bf2e90545417d3da1a674937257d00232ae36b8ffe8b19cdacac' 
  AND token = 'NFp8i9zwePNzYKLDybC6kx0psE8bdUW4dukzvYgCZvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}