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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a61b39cad538bcb16af92c6c55950453ac765437ffce64d068273e3e31e6467' 
  AND token = 'v7sGL92IGOFjW3xNz6ub8ntUo0GymSQ7zuAhyxEhAlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}