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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fbda20e3d2120ecffa1280cfc999d2a0ebefc6428dcbaf4db004eef92ea4b60' 
  AND token = '6X9B58euPJEBEYnWM2DVm9//F/G6x7FT0lSEtQYi5WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}