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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1afca1f3adc6be25ea9e67d125d49127776be7f35278e7d6cd6dde1e3b9590c' 
  AND token = 'PyW2ccRNj6kyhXvo2REhXo7Y6Yz9TZ/XJGSiOY1T7u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}