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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec2b9b709e675ffe10031d08c1a1022036a922998dadd6936ca011d85e5a8af' 
  AND token = 'sPICN1JzPITs+W+6VZS/D6qX153abNwcWcP7vhs+210=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}