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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f74eba5e3df6ed2eb037686255c53ffadf6b2b1d67e00bf7b5e275dc27101814' 
  AND token = 'QN8DhHTTKkBYeKaeRFOhFW08eP8m3zLVFEmetUYULlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}