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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404518e07b1e6de0307fe97ea6fa3c49422f964ac9ac47113076c5a48d7f76fc' 
  AND token = 'DKsr6KqFpYv5NLirp/Pfxy4fEuoFnKlt4ehs0SVVMVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}