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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b6b5fa2ea0fb3b94504714be8abe3f0e08e9da9178e9c56245f46431ac837b' 
  AND token = 'pUaL90OA6v4S6PafqKvpEFMmahqzr6eNJfStwbXSskQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}