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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545fa8f49d47d0e41035ce8063cf5ca42145276188b103cc54febd4b52fdd1bd' 
  AND token = 'Ca2TMyiFnx0/Y+6rP4+dozL3pHncPL0iFyfAdWQMC6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}